Nonmodifiable Osteoporosis



bone density peaks @ 30 years of age. women lose bone mass more rapidly men.



the important risk factors osteoporosis advanced age (in both men , women) , female sex; estrogen deficiency following menopause or surgical removal of ovaries correlated rapid reduction in bone mineral density, while in men, decrease in testosterone levels has comparable (but less pronounced) effect.
race: while osteoporosis occurs in people ethnic groups, european or asian ancestry predisposes osteoporosis.
heredity: family history of fracture or osteoporosis @ increased risk; heritability of fracture, low bone mineral density, relatively high, ranging 25 80%. @ least 30 genes associated development of osteoporosis.
those have had fracture @ least twice have fracture compared of same age , sex. menopause/hysterectomy predisposing factor.
build: small stature nonmodifiable risk factor associated development of osteoporosis.




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