History Hospital-acquired infection

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mortality rates 1841–1846 in 2 clinics documented semmelweis


in 1841, ignaz semmelweis, hungarian obstetrician working @ vienna maternity hospital. shocked death rate of women developed puerperal fever. documented infection 20 times higher in ward medical students delivering babies in next ward staffed midwifery students. medical students routinely working cadavers. compared rates of infection similar hospital in dublin, ireland , hypothesized medical students somehow infecting women after labor. instituted mandatory hand-washing in may 1847 , infection rates dropped dramatically. louis pasteur proposed germ theory of disease , began work on cholera in 1865 identifying microorganisms associated disease.








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